Polygenic scores:
In genetics, a polygenic score (PGS), also called a polygenic risk score (PRS), genetic risk score, or genome-wide score, is a number that summarises the estimated effect of many genetic variants on an individual’s phenotype, typically calculated as a weighted sum of trait-associated alleles. It reflects an individual’s estimated genetic predisposition for a given trait and can be used as a predictor for that trait. In other words, it gives an estimate of how likely an individual is to have a given trait only based on genetics, without taking environmental factors into account. Polygenic scores are widely used in animal breeding and plant breeding (usually termed genomic prediction or genomic selection) due to their efficacy in improving livestock breeding and crops. In humans, polygenic scores are typically generated from genome-wide association study (GWAS) data. [Wikipedia]
Noted in “Emerging Cracks In The Woke Elite,” Andrew Sullivan, The Weekly Dish:
Similarly, it was quite a shock to read in The New Yorker a fair and empathetic profile of an academic geneticist, Kathryn Paige Harden, who acknowledges a role for genetics in social outcomes. It helps that Harden is, like Freddie DeBoer, on the left; and the piece is strewn with insinuations that other writers on genetics, like Charles Murray, deny that the environment plays a part in outcomes as well (when it is clear to anyone who can read that this is grotesquely untrue). But if the readers of The New Yorker need to be fed distortions about some on the right in order for them to consider the unavoidable emergence of “polygenic scores” for humans, with their vast political and ethical implications, then that’s a step forward.
