{"id":7717,"date":"2017-01-19T17:29:12","date_gmt":"2017-01-19T23:29:12","guid":{"rendered":"http:\/\/huewhite.com\/umb\/?p=7717"},"modified":"2017-01-19T17:29:12","modified_gmt":"2017-01-19T23:29:12","slug":"word-of-the-day-79","status":"publish","type":"post","link":"https:\/\/huewhite.com\/umb\/2017\/01\/19\/word-of-the-day-79\/","title":{"rendered":"Word of the Day"},"content":{"rendered":"<p><em>Channelopathy<\/em>:<\/p>\n<blockquote><p>Several developmental diseases are caused by channelopathies, or malfunctions of our ion channels. They include Timothy syndrome and Andersen-Tawil syndrome, rare diseases that cause neurological, heart, and skull and facial defects. Even fetal alcohol syndrome, which can develop if a woman drinks during her pregnancy, can produce similar defects because alcohol blocks many of the same ion channels.<\/p><\/blockquote>\n<p>Noted in <i>\u201c<a href=\"https:\/\/www.newscientist.com\/article\/mg23331050-200-grow-with-the-flow-how-electricity-kicks-life-into-shape\/\" target=\"_blank\">Grow with the flow<\/a>,\u201d\u00a0<\/i>Jason Bittel, <em><strong>NewScientist<\/strong><\/em> (7 January 2017, paywall). An <a href=\"https:\/\/en.wikipedia.org\/wiki\/Ion_channel\" target=\"_blank\"><em>ion channel<\/em><\/a>:<\/p>\n<blockquote><p><b>Ion channels<\/b> are pore-forming <a title=\"Membrane protein\" href=\"https:\/\/en.wikipedia.org\/wiki\/Membrane_protein\">membrane proteins<\/a> whose functions include establishing a <a class=\"mw-redirect\" title=\"Resting membrane potential\" href=\"https:\/\/en.wikipedia.org\/wiki\/Resting_membrane_potential\">resting membrane potential<\/a>, shaping <a title=\"Action potential\" href=\"https:\/\/en.wikipedia.org\/wiki\/Action_potential\">action potentials<\/a> and other electrical signals by <a title=\"Gating (electrophysiology)\" href=\"https:\/\/en.wikipedia.org\/wiki\/Gating_(electrophysiology)\">gating<\/a> the flow of <a title=\"Ion\" href=\"https:\/\/en.wikipedia.org\/wiki\/Ion\">ions<\/a> across the cell membrane, controlling the flow of ions across <a title=\"Secretion\" href=\"https:\/\/en.wikipedia.org\/wiki\/Secretion\">secretory<\/a> and <a class=\"mw-redirect\" title=\"Epithelial cell\" href=\"https:\/\/en.wikipedia.org\/wiki\/Epithelial_cell\">epithelial cells<\/a>, and regulating cell volume.<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>Channelopathy: Several developmental diseases are caused by channelopathies, or malfunctions of our ion channels. They include Timothy syndrome and Andersen-Tawil syndrome, rare diseases that cause neurological, heart, and skull and facial defects. Even fetal alcohol syndrome, which can develop if a woman drinks during her pregnancy, can produce similar defects \u2026 <a class=\"continue-reading-link\" href=\"https:\/\/huewhite.com\/umb\/2017\/01\/19\/word-of-the-day-79\/\"> Continue reading <span class=\"meta-nav\">&rarr; <\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7717","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/7717","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/comments?post=7717"}],"version-history":[{"count":1,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/7717\/revisions"}],"predecessor-version":[{"id":7718,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/7717\/revisions\/7718"}],"wp:attachment":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/media?parent=7717"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/categories?post=7717"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/tags?post=7717"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}