{"id":37471,"date":"2022-10-02T11:43:25","date_gmt":"2022-10-02T16:43:25","guid":{"rendered":"http:\/\/huewhite.com\/umb\/?p=37471"},"modified":"2022-10-02T11:43:25","modified_gmt":"2022-10-02T16:43:25","slug":"those-unexpected-variables","status":"publish","type":"post","link":"https:\/\/huewhite.com\/umb\/2022\/10\/02\/those-unexpected-variables\/","title":{"rendered":"Those Unexpected Variables"},"content":{"rendered":"<p>Scientific research can be even harder than I thought:<\/p>\n<blockquote><p>Laboratory mice tend to be more stressed when they can smell men, making them behave differently in experiments depending on whether they are handled by a man or a woman. The finding raises important questions about past research using mice, since animal studies generally don\u2019t control for an experimenter\u2019s sex.<\/p>\n<p><a href=\"https:\/\/www.medschool.umaryland.edu\/profiles\/Gould-Todd\/\">Todd Gould<\/a>\u00a0at the University of Maryland began investigating this issue after his team couldn\u2019t replicate a simple lab result. The experiment involved a \u201cforced swim test\u201d, in which researchers place mice in a tank of water and see how long they keep trying to swim for. When they stop swimming, the researchers take them out, unharmed.<\/p>\n<p>In previous tests with male experimenters, mice tried to stay afloat for longer if they were given ketamine, an antidepressant. But when Polymnia Georgiou, a female researcher who was working in Gould\u2019s team, carried out the test, the mice gave up quickly regardless of whether they were given ketamine.<em> [&#8220;<\/em><a href=\"https:\/\/www.newscientist.com\/article\/2337160-the-sex-of-the-researcher-can-influence-results-of-mouse-experiments\/\" target=\"_blank\" rel=\"noopener\">The sex of the researcher can influence results of mouse experiments<\/a><em>,&#8221; Jonathan Moens, <\/em><strong>NewScientist<\/strong><em> (17 September 2022, paywall)]<\/em><\/p><\/blockquote>\n<p>In retrospect, it makes sense. But I still insist on being flabbergasted.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientific research can be even harder than I thought: Laboratory mice tend to be more stressed when they can smell men, making them behave differently in experiments depending on whether they are handled by a man or a woman. The finding raises important questions about past research using mice, since \u2026 <a class=\"continue-reading-link\" href=\"https:\/\/huewhite.com\/umb\/2022\/10\/02\/those-unexpected-variables\/\"> Continue reading <span class=\"meta-nav\">&rarr; <\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-37471","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/37471","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/comments?post=37471"}],"version-history":[{"count":1,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/37471\/revisions"}],"predecessor-version":[{"id":37472,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/37471\/revisions\/37472"}],"wp:attachment":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/media?parent=37471"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/categories?post=37471"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/tags?post=37471"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}