{"id":24822,"date":"2019-05-11T10:22:53","date_gmt":"2019-05-11T15:22:53","guid":{"rendered":"http:\/\/huewhite.com\/umb\/?p=24822"},"modified":"2019-05-11T10:22:53","modified_gmt":"2019-05-11T15:22:53","slug":"word-of-the-day-470","status":"publish","type":"post","link":"https:\/\/huewhite.com\/umb\/2019\/05\/11\/word-of-the-day-470\/","title":{"rendered":"Word Of The Day"},"content":{"rendered":"<p><em>Senolytics<\/em>:<\/p>\n<blockquote><p>A lot of the smart money is on a class of drugs called senolytics, which seek out and destroy worn-out cells that build up as we age. These cells have suffered some sort of irreversible damage and entered a state called senescence where they hit the emergency stop, hunker down and await destruction.<\/p>\n<p>This process probably evolved to stop cells from becoming cancerous. But it eventually backfires. \u201cSenescent cells are normally cleared out, but that goes wrong during ageing and they accumulate and cause tissue damage,\u201d says Partridge. The cells are like zombies: beyond repair, yet undead and causing havoc. They pump out a range of inflammatory proteins that are a major cause of inflammaging. \u201cSenescent calls are very bad for you,\u201d says\u00a0<a href=\"https:\/\/www.bioch.ox.ac.uk\/research\/cox\">Lynne Cox<\/a>, a biochemist at the University of Oxford. \u201cThey destroy the tissues around them.\u201d \u00a0<em>[<\/em>\u201c<a href=\"https:\/\/www.newscientist.com\/article\/mg24232270-100-anti-ageing-drugs-are-coming-that-could-keep-you-healthier-for-longer\/\" target=\"_blank\" rel=\"noopener noreferrer\">Anti-ageing drugs are coming that could keep you healthier for longer<\/a>,\u201d\u00a0<em>Graham Lawton, <strong>NewScientist<\/strong> (27 April 2019, paywall)]<\/em><\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>Senolytics: A lot of the smart money is on a class of drugs called senolytics, which seek out and destroy worn-out cells that build up as we age. These cells have suffered some sort of irreversible damage and entered a state called senescence where they hit the emergency stop, hunker \u2026 <a class=\"continue-reading-link\" href=\"https:\/\/huewhite.com\/umb\/2019\/05\/11\/word-of-the-day-470\/\"> Continue reading <span class=\"meta-nav\">&rarr; <\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-24822","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/24822","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/comments?post=24822"}],"version-history":[{"count":1,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/24822\/revisions"}],"predecessor-version":[{"id":24823,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/24822\/revisions\/24823"}],"wp:attachment":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/media?parent=24822"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/categories?post=24822"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/tags?post=24822"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}