{"id":17910,"date":"2018-10-14T11:20:55","date_gmt":"2018-10-14T16:20:55","guid":{"rendered":"http:\/\/huewhite.com\/umb\/?p=17910"},"modified":"2018-10-14T11:20:55","modified_gmt":"2018-10-14T16:20:55","slug":"word-of-the-day-413","status":"publish","type":"post","link":"https:\/\/huewhite.com\/umb\/2018\/10\/14\/word-of-the-day-413\/","title":{"rendered":"Word Of The Day"},"content":{"rendered":"<p><em>Hormesis<\/em>:<\/p>\n<blockquote><p>Hormesis is a term used by toxicologists to refer to a biphasic dose-response to an environmental agent characterized by a low dose stimulation or beneficial effect and a high dose inhibitory or toxic effect. In the fields of biology and medicine hormesis is defined as an adaptive response of cells and organisms to a moderate (usually intermittent) stress. Examples include ischemic preconditioning, exercise, dietary energy restriction and exposures to low doses of certain phytochemicals. Recent findings have elucidated the cellular signaling pathways and molecular mechanisms that mediate hormetic responses which typically involve enzymes such as kinases and deacetylases, and transcription factors such as Nrf-2 and NF-kappaB. As a result, cells increase their production of cytoprotective and restorative proteins including growth factors, phase 2 and antioxidant enzymes, and protein chaperones. A better understanding of hormesis mechanisms at the cellular and molecular levels is leading to and to novel approaches for the prevention and treatment of many different diseases.<em> [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18162444\" target=\"_blank\" rel=\"noopener\"><strong>PubMed.gov<\/strong><\/a>]<\/em><\/p><\/blockquote>\n<p>Noted in &#8220;<a href=\"http:\/\/blogs.discovermagazine.com\/crux\/2018\/10\/05\/epa-trump-administation-radiation-guidelines\/\" target=\"_blank\" rel=\"noopener\"><em>Is a Little Radiation Good For You? Trump Admin Steps Into Shaky Science<\/em><\/a>,&#8221; Nathaniel Scharping,\u00a0<strong><em>The Crux<\/em><\/strong>:<\/p>\n<blockquote><p>This week, the Associated Press reported that the Trump administration\u00a0may\u00a0be reconsidering that. The Environmental Protection Agency seemed to be looking at\u00a0<a href=\"https:\/\/apnews.com\/6a573b6b020e453c90ecd5e84aa23f57\" target=\"_blank\" rel=\"noopener\" data-vivaldi-spatnav-clickable=\"1\">raising\u00a0the levels of radiation\u00a0considered\u00a0dangerous to humans<\/a>\u00a0based on a controversial theory\u00a0rejected by mainstream scientists.\u00a0The theory suggests that a little radiation might actually be good for our bodies. In April, an\u00a0<a href=\"https:\/\/www.epa.gov\/newsreleases\/epa-administrator-pruitt-proposes-rule-strengthen-science-used-epa-regulations\" data-vivaldi-spatnav-clickable=\"1\">EPA press release announced the\u00a0proposal<\/a>\u00a0and included supporting\u00a0comments from a vocal proponent of the hypothesis, known as hormesis.\u00a0It prompted\u00a0<a href=\"https:\/\/www.washingtonpost.com\/opinions\/radiation-is-no-big-deal-just-ask-the-trump-administration\/2018\/10\/03\/4ef8b376-c750-11e8-b2b5-79270f9cce17_story.html?utm_term=.1641cb76e86f\" target=\"_blank\" rel=\"noopener\" data-vivaldi-spatnav-clickable=\"1\">critical opinion pieces<\/a>\u00a0and sparked worry among radiation safety advocates.<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>Hormesis: Hormesis is a term used by toxicologists to refer to a biphasic dose-response to an environmental agent characterized by a low dose stimulation or beneficial effect and a high dose inhibitory or toxic effect. In the fields of biology and medicine hormesis is defined as an adaptive response of \u2026 <a class=\"continue-reading-link\" href=\"https:\/\/huewhite.com\/umb\/2018\/10\/14\/word-of-the-day-413\/\"> Continue reading <span class=\"meta-nav\">&rarr; <\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-17910","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/17910","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/comments?post=17910"}],"version-history":[{"count":1,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/17910\/revisions"}],"predecessor-version":[{"id":17911,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/posts\/17910\/revisions\/17911"}],"wp:attachment":[{"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/media?parent=17910"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/categories?post=17910"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/huewhite.com\/umb\/wp-json\/wp\/v2\/tags?post=17910"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}